Fresh-frozen embryo transfer and embryo glue

IVF treatment has made it possible for childless couples to have their own genetically connected child. Infertility is a growing lifestyle problem these days. Couples have been finding ways of infertility treatment. Not everyone is in favor of child adoption and, hence, look for infertility treatment.

Infertility is caused due to several reasons. And, moreover, some reasons are unexplained. Hence, the couple has to undergo a succession of medical diagnosis to determine the actual reason of unattainable pregnancy in the couple. Reasons of infertility can persist in any of the partner or even in both of them. This is a phase where the couple, undergoing medication, has to make the major decisions of their life. IVF treatment corrects the causes of their infertility. The procedure includes retrieval of eggs and sperm separately from the female and male partner respectively, and make them fertilize in the laboratory. As the fertilization process is successful, the embryo formed out of such fertilization is introduced into the female’s uterus to create the pregnancy.

In many cases, couples go for egg donors or sperm donors to get the best and healthiest of all. This happens when the couple is unable to produce healthy sperm or eggs despite prolonged infertility treatment.

Embryo transfer is the next step after the eggs and sperm are fertilized in the laboratory. This can happen with the couple’s own sperm and eggs or can be borrowed from the donors. The embryo ultimately formed requires being introduced to the female’s uterus on the particular transfer date. In case the couple has opted to borrow frozen embryos, which are available with reputed IVF centers, the transfer procedure remains the same.

Let us here talk about the responsiveness of the frozen embryo, which many couples have been worried about. We have discussed cryopreservation in our previous articles. The procedure of cryopreservation is also applied to store the excess embryos to be offered to other childless couples. The process of such embryo transfer is similar to the fresh embryo transfer, and the frozen embryos are equally responsive as the fresh ones.

Now, the question that must be arising in the couple’s mind who are reading this article is, “Why going for the frozen embryo, when we can do it fresh?” So, let us talk more about it. Using frozen eggs not only gives you economic and time benefits, it saves you from the psychological depression that might arise in you due to repeated fertilization process. We have seen various couples who tend to lose confidence after few attempts of failed egg and sperm fertilization. Going for frozen eggs helps them to save time and spirit. It is also less expensive than the fresh procedure.

Here we can assure that the frozen embryos are all of the good qualities. There is a myth among the couples that the rejected embryos are usually the ones that are cryopreserved. This is a totally wrong conception. The excess embryos that are not required by some other couple, which is equally healthy as the one transferred to them, are stored for future use. The process of preservation is medically done by embryologists that stores it in its best state for a definite time period.

Use of Embryo Glue in Embryo Transfer

Embryologists take utmost care of the embryo transfer procedure as it is considered as the most sensitive, as well as critical part of the IVF treatment. Embryo glue is used in this procedure as a medium to smoothly transfer the embryo to the female uterus. It is a sticky substance (that’s where the name “glue” came from) that acts as a connector between the embryo tissues and the uterus. It secures the embryo tissues of any harm that might be caused during the procedure of transfer as it uses sharp surgical tools. Also, it keeps the embryos responsive throughout the transfer. Thus, a proper implantation is assured.

Embryo glue is a recent introduction in the IVF procedure. Yet, this application has acquired a great response from fertility experts and embryologists due to its proven success.

Ingredients of Embryo Glue and its benefits

Embryo glue is made of a rich blastocyst culture medium. It consists of hyaluronan and high concentration of recombinant human albumin. This blend creates a condition and warmth of the female uterus for the embryo and helps in its implantation.

Hyaluronan is a natural substance found in our bodies. It increases in proportion during the time of embryo implantation. This viscous fluid reduces the movement of the embryo inside the uterus. It is full of carbohydrate molecules that actively get involved in the first few stages of embryo implantation.

Basically, the substance is to protect the embryo from any external harm that might be caused by the atmosphere of the operation theatre or the surgical tools used in this procedure. Application of embryo glue has enhanced the success rates of pregnancy and, hence, is a more liked technique by embryologists and fertility doctors.

Overall success rate of pregnancy is recorded to be increased after the introduction of embryo glue in the IVF treatment. Patients, who are above the age of 35 are mostly benefitted from this as this age group is the one who suffers from unexplained infertility and failed implantation the most. This glue mimics the conditions of the uterus during implantation by maintaining the temperature and other required conditions. Thus, the embryos remain in its best condition throughout the implantation and make a successful pregnancy.

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