Assisted Embryo Hatching & IVF

The failure of In vitro fertilization (IVF) process is quite an exasperating experience not only for the females but also the desiring couples.  It happens because of the failure of embryo implantation in the uterine lining of the uterus.

For a female who has gone through an IVF failure may have poor chances for the IVF success.  In such a case, the experts in managing infertility may suggest a technique called assisted hatching.

What Is Assisted Hatching?

Once an egg gets fertilized in a lab, the process of division of the cell begins. During the initial phases of growth, the embryo is enclosed in a protein layer, called the zona pellicuda. For implanting it in the uterine lining, it has to come out of the zona pellucida and getting attached in the uterus walls.

Assisted hatching is a newly invented lab procedure that came into being when the experts in the infertility field found that the embryos having a lean zona pellucida had increased chances of implantation during the IVF procedure.

During assisted hatching, the embryologist utilizes the micromanipulation with the help of a microscope for creating a small opening in the zona pellucid.  This usually occurs on the 4th Day of the embryo grow when the embryo gets divided into 6-8 cells on an average.

With a holding pipette, the embryos are stabilized and the reverse side of the pipette contains a solution with an acid in it.   Thus, a small defect gets created in the zona pellucid. The embryos are afterwards washed for removing the excessive acidic solution and placed in the incubator for some hours for eventually transferring it to the uterus for implantation.

Who Should Use Assisted Hatching with IVF?

Assisted hatching is considered useful for the couples having a poor chance of success.  Their embryos are considered lacking adequate energy levels for completing the natural hatching process.

As per the medical experts in the field, the assisted hatching is suggested for the females:

  • In their advanced age (38 and above)
  • Having poor quality of embryos
  • Two or many failed IVF cycles

Does Assisted hatching increase the probability of IVF Success?

Assisted hatching is helpful in achieving the IVF success rate among those having poor chances of success.

Some researchers in the infertility field believe that with assisted hatching the embryo implant becomes easier in the females who happen to be of 38 in age and above or those who usually have a higher FSH level on the 3rd Day of their menstrual cycle or periods.  Having gone through several failed cycles of IVF, the couples can hope to see a silver lining of the IVF success with assisted hatching.

Assisted hatching is a difficult procedure.  And, the success of an IVF cycle may depend on the experience and expertise of the embryologist performing the procedure. It is worth talking to the Clinic how they perceive the success of the IVF cycle with assisted hatching method.

Is the procedure safe with IVF?

Some complications may arise with the assisted hatching. These complications may be linked with the harming of the embryo and the blastomeres.  The damaged blastomeres have the lesser viability of implanting. Apart from this, assisted hatching is linked to the running a risk of getting monozygotic twins (identical twins).

It is worth discussing the benefits and risks of assisted hatching with an infertility expert.

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